Reducing chest pain depends on the cause of the chest pain.
If you are having pain from GERD, then a medication called PPI (proton pump inhibitor) can help. These include medications like pantoprazole.
However, oftentimes the pain is related to a blood flow issue to the heart. In that case, testing would need to be done to make sure it is not a heart attack. Some patient have known heart disease and have chronic chest pains that are stable (stable angina). In that case, certain medications can be use that help reduce or eliminate pain that can impair quality of life. Such medications include beta blockers (like metoprolol), venodilators (like isosorbide mononitrate or IMDUR), and other medications like Ranolazine.
Having an attentive heart doctor look at your medications can be an important step in reducing your chest pain symptoms.